WebJun 26, 2016 · When do you take it. I'm 2 1/2 months on Cymbalta this time round. You asked the last time I took Cymbalta I was on it for around 9 months then stopped over a 2 week period. I never had a problem stopping the last time. I find it helps a lot with depression and anxiety. So overal I'm happy. Feel free to ask me anything! You could give more time ... WebDr. Barbara A Majeroni answered. Specializes in Family Medicine. Morning is better: Taken in the evening, Cymbalta ( duloxetine) can cause insomnia, so it is better to take it in the morning. Created for people with ongoing healthcare needs but benefits everyone. Learn how we can help.
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