Nphs2 cre
Web24 jul. 2012 · The Nphs2-Cre mouse line (3) expresses Cre-recombinase tran-script under control of a 2.5-kb mouse podocyte-specific podocin promoter. The Arnt flox/flox mice were kindly provided by Dr. Frank J. Gonzalez (22). To generate mice with podocyte-selective deletion of Arnt, Nphs2-Cre mice were bred to Arnt flox/flox homozygotes. Web实验小鼠是目前应用最为广泛的一种实验动物，在探寻基因基础功能，疾病发病机制以及药物临床前筛选等方面有着十分重要的作用。 其原因在于小鼠和人的基因具有极高的相似 …
Nphs2 cre
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WebNPHS2 pathogenic variants are the most common podocyte gene defects. Yet, pathogenic variants are found only in a minority of SRNS patients. No homozygotes or compound heterozygotes were observed in 377 biopsy confirmed late-onset FSGS [52].In three large worldwide analyses, NPHS2 pathogenic variants were found in roughly 10% of the … Web9 sep. 2024 · The NPHS2 gene encodes Podocin, which is specifically expressed in podocytes. In their paper, Balkawade et al. observed a thickening of the glomerular basement membrane (GBM) in 24-week-old NPHS2-Cre mice, which was not associated with any modification of glomerular/renal function.
WebNPHS2-cre. 2024-11-19. B6.Cg-Tg(NPHS2-cre)295Lbh. 品系编号：GAP1021. 品系简称：NPHS2-cre. 品系特点：. NPHS2-Cre 小鼠可存活且可生育，Cre 重组酶的表达通过人 … WebNPHS2 pathogenic variants are the most common podocyte gene defects. Yet, pathogenic variants are found only in a minority of SRNS patients. No homozygotes or compound …
Web29 sep. 2024 · NPHS2-Cre + Meg3 flox/flox and Meg3 +/+ mice were randomly divided into diabetic and non-diabetic groups, respectively. All the following animal experiments were evaluated in a blinded manner. Webindividual cell types. To further validate the clustering analysis results, we used Nphs2. Cre. mTmG, Scl. Cre. mTmG and Cdh16. Cre. mTmG mice as reporter lines to mark …
WebFirst, Nphs2 encodes podocin, an essential component of the slit diaphragm, a cell-cell junctional structure between adjacent podocytes, which is one of the most important …
http://www.informatics.jax.org/allele/MGI:4442436 tirschenreuth porzellan bavariaWebNphs2 Also Known As Podocin Cre Mice, supplied by The Jackson Laboratory, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS … tirschenreuth seenarioWeb008523 129S6.Cg-Tg(NPHS2-cre)295Lbh/BroJ These 129S6 Podocin-Cre mice (harboring the p2.5P-Cre transgene) have expression of Cre recombinase directed to podocytes … tirschenreuth teststationWeb8 mei 2024 · Mice carrying the NPHS2-Cre transgene were identified via a PCR-based protocol using the primers (Integrated DNA Technologies, Coralville, IA) and probes (Life … tirschenreuth tea cup and saucerWeb1 mrt. 2024 · Of these significant, differentially regulated genes, 139 were up-regulated and 91 were down-regulated in glomeruli of NPHS2-Cre +/+ mice as compared with that … tirschenreuth the bolton 4677Web008205 B6.Cg-Tg(NPHS2-cre)295Lbh/J These transgenic mice (commonly referred to as podocin-Cre mice) have expression of Cre recombinase directed to podocytes within … tirschenreuth tourist infoWeb29 apr. 2024 · The phenotypes of extrarenal Cre activity were more pronounced than that of NPHS2-Cre, but DNA damage and epithelial apoptosis appear to be common Cre … tirschenreuth tea set