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WebJan 6, 2024 · How to take tadalafil. For the ‘on-demand’ dose, 10 mg or 20 mg should be taken at least 30 minutes before you plan to have sex (it may still work 36 hours later). Do … WebMost common side effects (affect 1 to 10 in every 100 users) include: a stuffy/blocked nose. flushed (red) face. headache. indigestion. muscles aches. pain in your arms, legs or back. Uncommon side effects (affect 1 to 10 in every 1000 users) include: a prolonged erection.

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