Webphenotype: [noun] the observable properties of an organism that are produced by the interaction of the genotype and the environment. WebSubtyping ciliopathy patients with phenotypic similarity showed concordances with expert knowledge. Similarity metrics applied to rare disease offer new perspectives in a translational context that may help to recruit patients for research, reduce the length of the diagnostic journey, and better understand the mechanisms of the disease.
phenotypic - WordReference.com 英汉词典
WebFeb 19, 2015 · Semantic similarity measures over phenotype ontologies have been demonstrated to provide a powerful approach for the analysis of model organism phenotypes, the discovery of animal models of human disease, novel pathways, gene functions, druggable therapeutic targets, and determination of pathogenicity. We have … Websimilarity, resemblance, analogy, likeness. 这些名词均含"相似，类似"之意。 similarity ： 指不同的人或事物在外表、特征、程度或性质等方面有某些相似之处。; resemblance ： 指外观或性质有相似之处。; analogy ： 指外表或实质均不相同的事物对比之下的类似之处。; likeness ： 普通用词，指人或物从外观看去 ... how many feet are 169 inches
Semantic Similarity Analysis Reveals Robust Gene ... - ScienceDirect
WebFeb 25, 2011 · Homoplasy is similarity that is the result not of simple ancestry, but of either reversal to an ancestral trait in a lineage or of independent evolution (convergence, similarity resulting from different developmental genetic mechanisms; or parallelism, similarity resulting from the same developmental genetic mechanisms) ( Fig. 1 ). WebOct 15, 2024 · Results The human phenotype ontology (HPO) together with the information content (IC) are widely used for phenotypic similarity evaluation. Here, we introduce PSEA, a new phenotypic similarity evaluation tool capable of quantifying groups of HPO terms unbiasedly. By comparing with other methods, PSEA show optimal performance and show … WebThe similarity metrics were computed on both data sources, and were evaluated with two … how many feet are 108 inches